What is the appropriate IV solution to prime tubing for a transfusion of packed RBCs?

The appropriate intravenous solution to prime the tubing for a transfusion of packed red blood cells (RBCs) is 0.9% sodium chloride, commonly known as normal saline. This solution is isotonic and compatible with blood products, making it the ideal choice for preparing blood transfusion equipment. Normal saline helps to maintain osmotic balance and ensures that the infused blood cells do not hemolyze or undergo damage due to osmotic pressure.

Using 0.9% sodium chloride also helps to prevent any adverse reactions that can occur if incompatible fluids are introduced into the system during a blood transfusion. For example, dextrose solutions could cause red blood cells to lyse, and other solutions, like Lactated Ringer’s or half-strength saline, may introduce electrolytes or components that can interact negatively with the blood components. Thus, 0.9% sodium chloride is specifically recommended to ensure safe and effective transfusion practice.